The combination of diabetes and hypertension is not only common, and increasingly so, but is responsible for a substantial proportion of all cardiovascular morbidity and mortality around the world. ...

Cardiovascular disease (CVD) mortality began to decline in the United States even before widespread use of antihypertensive therapy. By that time, a direct linear relationship between blood pressure ...

We showed recently that mononuclear phagocyte system (MPS) cells provide a buffering mechanism for salt-sensitive hypertension by driving interstitial lymphangiogenesis, modulating interstitial Na+ ...

Background: Self blood pressure monitoring at home may improve blood pressure control and patients' compliance with treatment, but its implementation in daily practice faces difficulties. ...

The use of placebo in hypertension studies, although largely debated at the beginning of the antihypertensive therapy story [1,2], has come to be widely accepted [2] and has been instrumental in ...

Objective: A few population-based studies have shown that high-normal blood pressure clusters with other cardiovascular risk factors. Increased inflammation, endothelial dysfunction, oxidative ...

This document summarizes the available evidence and provides recommendations on the use of home blood pressure monitoring in clinical practice and in research. It updates the previous recommendations ...

The proteinase-activated receptor 2 (PAR-2) expression is increased in endothelial cells derived from women with preeclampsia, characterized by widespread maternal endothelial damage, which occurs as ...

Angiotensin II (AngII)–induced hypertension in experimental animals has been proposed to be attributed in part to activation of the sympathetic nervous system. This sympathetic activation appears to ...

In animals, electric field stimulation of carotid baroreceptors elicits a depressor response through sympathetic inhibition. We tested the hypothesis that the stimulation acutely reduces sympathetic ...

Abstract & Background  Oxidized lipoproteins and antioxidized low-density lipoprotein (anti-oxLDL) antibodies (Abs) have been detected in plasma in response to blood pressure (BP) ...

Hypertensive patients receiving long-term monotherapy with ACE inhibitors, angiotensin-receptor blockers (ARBs), or beta blockers were less likely to develop atrial fibrillation (AF) than those who ...

New statistical projections suggest that slashing salt in the US diet by 3 g per day would have huge benefits, reducing the annual number of new cases of coronary heart disease, strokes, and MIs and ...

Introducción Las actividades de atención farmacéutica son un recurso para aumentar el grado de control de pacientes con enfermedades crónicas. El objetivo de este estudio es evaluar la eficacia de ...

Background  Patients with aortic valve sclerosis (AVS) have an increased risk of cardiovascular events. Patients with atherosclerotic renal artery stenosis (RAS) develop resistant hypertension ...